2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-161384
    WJM-715
    		Inhibitor
    WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM.
    WJM-715
  • HY-B1751F
    Quinidine gluconic acid
    		Inhibitor
    Quinate is an antiarrhythmic agent. Quinate is a potent, orally active, selective cytochrome P450db inhibitor. Quinate is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinate can be used for malaria research.
    Quinidine gluconic acid
  • HY-162155
    Diarctigenin
    		Inhibitor
    Diarctigenin is a selective Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS) inhibitor. Diarctigenin can be used for the research of tropical disease.
    Diarctigenin
  • HY-15648H
    GSK-J5 hydrochloride
    		Inhibitor
    GSK-J5 hydrochloride is a cell-permeable?ester derivative of?GSK J2 (HY-15648A), inactive. GSK-J5 hydrochloride is also an?isomer of GSK-J4 (HY-15648B) and often used as a negative group.
    GSK-J5 hydrochloride
  • HY-118448R
    2,4-Diacetylphloroglucinol (Standard)
    2,4-Diacetylphloroglucinol (Standard) is the analytical standard of 2,4-Diacetylphloroglucinol (HY-118448). This product is intended for research and analytical applications. 2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings.
    2,4-Diacetylphloroglucinol (Standard)
  • HY-W268334
    1,2,3,4-Tetrahydronorharman-1-one
    		Inhibitor
    1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge.
    1,2,3,4-Tetrahydronorharman-1-one
  • HY-N8585
    Neoprocurcumenol
    		Inhibitor
    Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC50 and LC 90 values of 13.69 and 23.92 ppm, respectively.
    Neoprocurcumenol
  • HY-B0508S
    Ornidazole-d5
    		Inhibitor
    Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
    Ornidazole-d<sub>5</sub>
  • HY-128398
    CpCDPK1/TgCDPK1-IN-2
    		Inhibitor
    CpCDPK1/TgCDPK1-IN-2 (Compound 7r) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 12 and 5 nM, respectively. CpCDPK1/TgCDPK1-IN-2 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection.
    CpCDPK1/TgCDPK1-IN-2
  • HY-149073
    TSC26
    		Inhibitor
    TSC26, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 175 nM, a pIC50 of 6.76 and a pKa of 6.6. TSC26 has the potential for parasitic diseases research.
    TSC26
  • HY-135666
    DHODH-IN-8
    		Inhibitor
    DHODH-IN-8 (Compound 27) is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50s of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively. DHODH-IN-8 has antimalarial activity.
    DHODH-IN-8
  • HY-N1219
    Stephanine
    		Inhibitor
    Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer.
    Stephanine
  • HY-121154
    Hexachloroparaxylene
    Hexachloroparaxylene could be used in the study of in fascioliasis in swine.
    Hexachloroparaxylene
  • HY-155025
    Antitrypanosomal agent 14
    		Inhibitor
    Antitrypanosomal agent 14 (Compound 1) is a T. brucei inhibitor (EC50: 0.47 μM). Antitrypanosomal agent 14 inhibits TbGSK3 with an IC50 of 12 μM. Antitrypanosomal agent 14 can be used for the research of Human African trypanosomiasis.
    Antitrypanosomal agent 14
  • HY-168429
    3HKT-IN-1
    		Inhibitor
    3HKT-IN-1 (Compound 17122279) is an Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) inhibitor. 3HKT-IN-1 can be used for Malaria research.
    3HKT-IN-1
  • HY-146049
    Antitrypanosomal agent 4
    		Inhibitor
    Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively. Antitrypanosomal agent 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Antitrypanosomal agent 4
  • HY-121187
    BiPNQ
    		Inhibitor
    BiPNQ is a potent inhibitor of Trypanosoma cruzi, the causative agent of Chagas disease.
    BiPNQ
  • HY-115364S
    Parbendazole-d3
    		Inhibitor
    Parbendazole-d3 is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.
    Parbendazole-d<sub>3</sub>
  • HY-137141
    16-Keto Aspergillimide
    		Inhibitor
    16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664.
    16-Keto Aspergillimide
  • HY-107034
    Moxipraquine
    		Inhibitor
    Moxipraquine is a potent insecticide against Trypanosoma cruzi. Moxipraquine effectively inhibits Leishmania major, L. mexicana mexicana and L. brasiliensis panamensis but not L.b. brasiliensis .
    Moxipraquine
Parasite Isoform Comparison

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